Computational detection of natural selection in gene family expansion and contraction

Here we use a model of stochastic birth and death for mapping gene family evolution onto a phylogeny, and show that it can be efficiently applied to multispecies comparisons. The model offers the opportunity for researchers to make stronger inferences regarding the role of natural selection and changing duplication and deletion rates in gene family expansion or contraction. The work is performed as a part of the first author’s MS thesis under the second author’s supervision.

Từ khóa: Tạo chí tin học, Điều khiển học, Computational detection, atural selection, Gene family expansion, Cơ sở thống kê